MST Nutrition™ Folate 400 Quatrefolic® is a high-quality dietary supplement that provides biologically active folate in the form of Quatrefolic®. Quatrefolic® is the glucosamine salt of 5-methyltetrahydrofolate (5-MTHF), which the body can use immediately without requiring further conversion.

Contents: 90 capsules per bottle
Dosage: Each capsule contains 400 mcg of Quatrefolic®
Ingredients: Bulking agents (microcrystalline cellulose, sodium carboxymethylcellulose), coating agent (hydroxypropyl methylcellulose), folic acid (as (6S)-5-methyltetrahydrofolate-glucosamine salt). Folic acid is added in the form of Quatrefolic®.

The recommended dose is one capsule per day, preferably taken with a meal and plenty of liquid. This dosage covers the daily folate requirements and may help prevent folate deficiency.

Folate vs. Folic Acid

Folate:

• Natural: Folate is the natural form of vitamin B9, found in foods such as leafy green vegetables, fruits, nuts, and legumes.

• Bioavailability: Folate is directly used by the body and does not require conversion to be active.

• Functions: It participates in DNA synthesis, cell division, and red blood cell production.

Folic Acid:

• Synthetic: Folic acid is the synthetic form of vitamin B9, found in dietary supplements and fortified foods such as cereals and bread.

• Conversion: Folic acid must be converted in the body by the enzyme methylenetetrahydrofolate reductase (MTHFR) into its active form (5-methyltetrahydrofolate or 5-MTHF).

• Conversion Issues: Some people have genetic variations that reduce the efficiency of this conversion, making folic acid less effective.
  
  
  

What is 5-methyltetrahydrofolate (5-MTHF)?

5-methyltetrahydrofolate (5-MTHF) is the bioactive form of folate directly usable by the body. It is one of the most important and best-absorbed forms of folate, offering many advantages over synthetic folic acid.

Properties and Benefits of 5-MTHF:

Direct Availability:

• 5-MTHF does not need to be converted by the MTHFR enzyme, which is crucial for people with MTHFR mutations.

Support for Homocysteine Reduction:

• 5-MTHF plays a key role in homocysteine metabolism, helping to reduce high blood levels and lower the risk of cardiovascular diseases.

Essential During Pregnancy and for Cell Division:

• 5-MTHF is indispensable for pregnant women as it supports DNA synthesis and cell division, promoting healthy fetal growth and development.

Better Bioavailability and Effectiveness:

• Studies show that 5-MTHF has superior bioavailability compared to synthetic folic acid, meaning the body absorbs and uses it more efficiently.