MST Nutrition™ Folate 400 Quatrefolic® is a high-quality dietary supplement that provides biologically active folate in the form of Quatrefolic®. Quatrefolic® is the glucosamine salt of 5-methyltetrahydrofolate (5-MTHF), which the body can use immediately without requiring further conversion.

Contents: 90 capsules per bottle
Dosage: Each capsule contains 400 mcg of Quatrefolic®
Ingredients: Bulking agent (microcrystalline cellulose, sodium carboxymethylcellulose), coating agent (hydroxypropyl methylcellulose), folic acid (in the form of (6S)-5-methyltetrahydrofolate-glucosamine salt). L’folic acid is added in the form of Quatrefolic®.

The recommended dose is one capsule per day, preferably taken with a meal and plenty of liquid. This dosage covers daily folate requirements and may help prevent folate deficiency.

Folate vs. Folic Acid

Folate:

• Natural: Folate is the natural form of vitamin B9, found in foods such as leafy green vegetables, fruits, nuts, and legumes.

• Bioavailability: Folate is used directly by the body and does not need to be converted to become active.

• Functions: It is involved in DNA synthesis, cell division, and the production of red blood cells.

Folic acid:

• Synthetic: L folic acid is the synthetic form of vitamin B9, found in supplements and fortified foods such as cereals and bread.

• Conversion: L folic acid must be converted in the body by the enzyme methylenetetrahydrofolate reductase (MTHFR) into its active form (5-methyltetrahydrofolate or 5-MTHF).

• Conversion problems: Some people have genetic variations that reduce the efficiency of this conversion, making folic acid less effective.
  
  
  

What is 5-methyltetrahydrofolate (5-MTHF)?

5-methyltetrahydrofolate (5-MTHF) is the bioactive form of folate that the body can use directly. It is one of the most important and best-absorbed forms of folate, offering many benefits over synthetic folic acid.

Properties and benefits of 5-MTHF:

Direct availability:

• 5-MTHF does not need to be converted by the MTHFR enzyme, which is crucial for people with MTHFR mutations.

Support for reducing homocysteine:

• 5-MTHF plays a key role in homocysteine metabolism, helping reduce high blood levels and lower the risk of cardiovascular disease.

Essential during pregnancy and for cell division:

• 5-MTHF is essential for pregnant women because it supports DNA synthesis and cell division, promoting healthy fetal growth and development.

Improved bioavailability and effectiveness:

• Studies show that 5-MTHF has greater bioavailability than synthetic folic acid, meaning the body absorbs and uses it more effectively.